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    Ability To Utilize Energy Of Various Nutrients Can Be Affected By Genetic Differences: Study

    Genetic Differences
    Inam Ansari
    April24/ 2022

    Washington: Minor genetic differences can affect the ability to utilize the energy of various nutrients, according to a new study by the University of Helsinki. The findings of the study were published in the journal 'Nature Communications.' The study showed how nutritional planning based on genetic data could promote the development of personalized nutrition for health. In an international collaborative study, researchers from Australia, Denmark, and Finland investigated how individuals of the same population differ in their ability to survive on various diets. The researchers utilized a genetic reference panel consisting of roughly 200 closely related fruit fly strains (Drosophila melanogaster). The flies were fed six different diets containing high concentrations respectively of protein, sugar, starch, coconut oil or lard, or a combination of sugar and lard. The study of fruit flies found that small genetic differences affected the flies' ability to use the energy of various nutrients. "Unexpectedly we found that the fruit fly strains differed considerably, for example, in their ability to survive on a high-sugar diet. What makes this particularly surprising is the fact that the food consumed by fruit flies in nature contains a lot of sugars," said Essi Havula, now a postdoctoral researcher at the University of Helsinki and the lead author of the study. "The genes that regulate metabolism have been conserved well in evolution, which is why we can learn a lot about human metabolism through studies carried out with fruit flies," Havula added. In genetic analyses, the researchers identified a number of genes that contributed to the ability of flies to tolerate sugar. Most of these genes are found also in humans and have been sug ...

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