Tag : Lifespan

    Researchers Discover Link Between Food, Eye Health And Lifespan

    Food, Eye Health
    Inam Ansari
    June8/ 2022

    California: In Drosophila, researchers from the Buck Institute have discovered a link between nutrition, circadian rhythms, eye health, and lifespan for the first time. They also discovered that activities in the fly eye are actually driving the ageing process. The research has been published in the journal, "Nature Communications" Previous studies have shown in humans that there is an association between eye disorders and poor health. "Our study argues that it is more than correlation: dysfunction of the eye can actually drive problems in other tissues," said senior author and Buck Institute Professor Pankaj Kapahi, PhD, whose lab has demonstrated for years that fasting and caloric restriction can improve many functions of the body. "We are now showing that not only does fasting improve eyesight, but the eye actually plays a role in influencing lifespan." "The finding that the eye itself, at least in the fruit fly, can directly regulate lifespan was a surprise to us," said lead author, Brian Hodge, PhD, who did his postdoctoral studies in Kapahi's lab. The explanation for this connection, Hodge said, lies in circadian "clocks," the molecular machinery within every cell of every organism, which has evolved to adapt to daily stresses, such as changes in light and temperature caused by the rising and setting of the sun. These 24-hour oscillations - circadian rhythms - affect complex animal behaviours, such as predator-prey interactions and sleep/wake cycles, down to fine-tuning the temporal regulation of molecular functions of gene transcription and protein translation. In 2016 Kapahi's lab published a study in Cell Metabolism showing that fruit flies on a restricted diet had significant changes in their circadian rhythms in addition t ...

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