Tag : Clogged

    Short Night-Time Sleep Doubles Risk Of Clogged Leg Arteries: Research

    Short Night-Time Sleep
    Inam Ansari
    March16/ 2023

    Washington: Sleeping less than five hours each night is linked to a 74 per cent increased risk of developing peripheral arterial disease (PAD) compared to sleeping seven to eight hours, according to research published in the European Heart Journal - Open, an ESC journal. "Our study suggests that sleeping for seven to eight hours a night is a good habit for lowering the risk of PAD," said study author Dr. Shuai Yuan of the Karolinska Institute, Stockholm, Sweden. More than 200 million people globally have peripheral artery disease (PAD),2 where arteries in the legs are clogged, restricting blood flow and increasing the risk of stroke and heart attack. Dr. Yuan said: "Insufficient night-time sleep and daytime napping have previously been associated with a raised risk of coronary artery disease which, like PAD, is caused by clogged arteries. In addition, sleeping problems are among the top ranked complaints in PAD patients. There are limited data on the impact of sleep habits on PAD and vice versa, and our study aimed to fill that gap." The study included more than 650,000 participants and was conducted in two parts.3 First, the researchers analysed the associations of sleep duration and daytime napping with the risk of PAD. In the second part, the investigators used genetic data to perform naturally randomised controlled trials - called Mendelian randomisation - to examine causality of the associations. Dr. Yuan said: "Observational analyses are limited by reverse causality - meaning that if an association between sleep habits and PAD is found, we cannot be certain if sleep habits caused PAD or having PAD caused the sleep habits. Mendelian randomisation is a robust method for evaluating causality and provides more certainty about the r ...

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